Take the N1 North to Pretoria.
Take split from N1 to Pietersburg/Polokwane.
After the 'Zambezi-offramp' (north of Pretoria) take N4 toll road to Rustenburg.
Once on the N4 continue, this is a toll road to Rustenburg, Swartruggens, Groot Marico and Zeerust.
In Zeerust, turn right at President street onto the R 47/49 to Gaborone.
You'll reach the first Madikwe Game Reserve gate approximately 90km from Zeerust.
Pass all the gates indicating Madikwe and travel to the Kopfontein border post going towards Gaborone.
Turn right onto the Derdepoort Gate road, just before the border post and follow the road for approximately 10 km to the Tau lodge gate.